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RAP80 and RNF8, key players in the recruitment of repair proteins to DNA damage sites
Chromosomal double-strand breaks (DSBs) in eukaryotes provoke a rapid, extensive modification in chromatin flanking the breaks. The DNA damage response (DDR) coordinates activation of cell cycle checkpoints, apoptosis, and DNA repair networks, to ensure accurate repair and genomic integrity. The che...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2749678/ https://ncbi.nlm.nih.gov/pubmed/18550271 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2008.04.046 |
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