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Deciphering the function of canonical Wnt signals in development and disease: conditional loss- and gain-of-function mutations of β-catenin in mice

Wnt signaling is one of a handful of powerful signaling pathways that play crucial roles in the animal life by controlling the genetic programs of embryonic development and adult homeostasis. When disrupted, these signaling pathways cause developmental defects, or diseases, among them cancer. The ga...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Grigoryan, Tamara, Wend, Peter, Klaus, Alexandra, Birchmeier, Walter
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749675/
https://ncbi.nlm.nih.gov/pubmed/18765787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1686208
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