RXP-E: A CX43-BINDING PEPTIDE THAT PREVENTS ACTION POTENTIAL PROPAGATION BLOCK

Gap junctions (GJs) provide a low-resistance pathway for cardiac electrical propagation. The role of GJ regulation in arrhythmia is unclear, partly due to limited availability of pharmacological tools. Recently, we showed that a peptide called “RXP-E” binds to the carboxyl terminal of connexin43 (Cx...

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Main Authors: Lewandowski, Rebecca, Procida, Kristina, Vaidyanathan, Ravi, Coombs, Wanda, Jalife, Jose, Nielsen, Morten S., Taffet, Steven M., Delmar, Mario
Format: Artigo
Jezik:Inglês
Izdano: 2008
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749574/
https://ncbi.nlm.nih.gov/pubmed/18669919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.108.179069
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