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Oxidative stress sensitizes bladder cancer cells to TRAIL-mediated apoptosis by downregulating anti-apoptotic proteins
PURPOSE: TRAIL, an endogenous protein involved in immunosurveillance and a novel drug in clinical trials, is of particular interest as a cancer therapeutic because it can induce apoptosis in cancer cells but not in normal cells. Since some cancers develop resistance to TRAIL, safe and effective meth...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2749573/ https://ncbi.nlm.nih.gov/pubmed/19625063 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.juro.2009.05.005 |
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