Multiple Novel Loci, Including Those Related to Crohn’s Disease, Psoriasis and Inflammation, Identified in a Genome-Wide Association Study of Fibrinogen in 17,686 Women: the Women’s Genome Health Study

BACKGROUND: Fibrinogen is a multifunctional circulating glycoprotein involved in wound-healing, thrombosis, platelet aggregation and inflammation, and elevated levels predict vascular disease. Despite evidence of such crucial biological functions and moderate heritability, comprehensive analysis of...

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Detalhes bibliográficos
Main Authors: Danik, Jacqueline S., Pare, Guillaume, Chasman, Daniel I., Zee, Robert Y.L., Kwiatkowski, David J., Parker, Alex, Miletich, Joseph P., Ridker, Paul M
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749513/
https://ncbi.nlm.nih.gov/pubmed/20031577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGENETICS.108.825273
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