MicroRNA Profiling of BRCA1/2 Mutation-Carrying and Non-Mutation-Carrying High-Grade Serous Carcinomas of Ovary

BACKGROUND: MicroRNAs (miRNA) are 20∼25 nucleotide non-coding RNAs that inhibit the translation of targeted mRNA, and they have been implicated in the development of human malignancies. High grade serous ovarian carcinomas, the most common and lethal subtype of ovarian cancer, can occur sporadically...

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Détails bibliographiques
Auteurs principaux: Lee, Cheng-Han, Subramanian, Subbaya, Beck, Andrew H., Espinosa, Inigo, Senz, Janine, Zhu, Shirley X., Huntsman, David, van de Rijn, Matt, Gilks, C. Blake
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2009
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749450/
https://ncbi.nlm.nih.gov/pubmed/19798417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007314
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