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Highly parallel measurements of interaction kinetic constants with a microfabricated optomechanical device
We used mechanical trapping of molecular interactions to demonstrate a highly parallel approach to measure the kinetics of biomolecular interactions. This approach consumes 25 fmol of material per measurement and permits 320 measurements in a single experiment. We measured association and dissociati...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Institute of Physics
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2749446/ https://ncbi.nlm.nih.gov/pubmed/19777091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.3211382 |
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