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A single-photon counting detector for increased sensitivity in two-photon laser scanning microscopy

We present the use and characterization of a photon counting detector for increased sensitivity at low signal levels in fluorescence laser scanning microscopy (LSM). Conventional LSM PMT detectors utilize analog current integration and thus suffer from excessive noise at low signal levels, introduce...

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Hlavní autoři: Benninger, Richard K.P., Ashby, William J., Ring, Elisabeth A., Piston, David W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749309/
https://ncbi.nlm.nih.gov/pubmed/19079484
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