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A single-photon counting detector for increased sensitivity in two-photon laser scanning microscopy
We present the use and characterization of a photon counting detector for increased sensitivity at low signal levels in fluorescence laser scanning microscopy (LSM). Conventional LSM PMT detectors utilize analog current integration and thus suffer from excessive noise at low signal levels, introduce...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2749309/ https://ncbi.nlm.nih.gov/pubmed/19079484 |
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