PET Imaging of D(2/3) agonist binding in healthy human subjects with the radiotracer [(11)C]-N-propyl-nor-apomorphine (NPA): preliminary evaluation and reproducibility studies

OBJECTIVE: (-)-N-[(11)C]-Propyl-norapomorphine (NPA) is a full dopamine D(2/3) receptor agonist radiotracer suitable for imaging D(2/3) receptors configured in a state of high affinity for agonists using Positron Emission Tomography (PET). The aim of the present study was to define the optimal analy...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Narendran, Rajesh, Frankle, W. Gordon, Mason, N. Scott, Laymon, Charles M., Lopresti, Brian J, Price, Julie C., Kendro, Steve, Vora, Shivangi, Litschge, Maralee, Mountz, James M., Mathis, Chester A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749304/
https://ncbi.nlm.nih.gov/pubmed/19301416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/syn.20633
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