Phenotypic Characterization of Mice Heterozygous for a Null Mutation of Glutamate Carboxypeptidase II

Glutamate is the major excitatory neurotransmitter in the mammalian central nervous system. Disturbed glutamate signaling resulting in hypofunction of NMDA receptors has been implicated in the pathophysiology of schizophrenia. Glutamate Carboxypeptidase II (GCP II) hydrolyzes N-acetyl-alpha L-aspart...

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Autori principali: Han, Liqun, Picker, Jonathan D., Schaevitz, Laura R., Tsai, Guochuan, Feng, Jiamin, Jiang, Zhichun, Chu, Hillary C., Basu, Alo C., Berger-Sweeney, Joanne, Coyle, Joseph T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749286/
https://ncbi.nlm.nih.gov/pubmed/19347959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/syn.20649
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