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Silencing of ErbB3/ErbB2 Signaling by Immunoglobulin-like Necl-2
ErbB2 and ErbB3, members of the EGF receptor/ErbB family, form a heterodimer upon binding of a ligand, inducing the activation of Rac small G protein and Akt protein kinase for cell movement and survival, respectively. The enhanced ErbB3/ErbB2 signaling causes tumorigenesis, invasion, and metastasis...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2749152/ https://ncbi.nlm.nih.gov/pubmed/19561085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.025155 |
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