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Silencing of ErbB3/ErbB2 Signaling by Immunoglobulin-like Necl-2

ErbB2 and ErbB3, members of the EGF receptor/ErbB family, form a heterodimer upon binding of a ligand, inducing the activation of Rac small G protein and Akt protein kinase for cell movement and survival, respectively. The enhanced ErbB3/ErbB2 signaling causes tumorigenesis, invasion, and metastasis...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kawano, Satoshi, Ikeda, Wataru, Kishimoto, Megumi, Ogita, Hisakazu, Takai, Yoshimi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749152/
https://ncbi.nlm.nih.gov/pubmed/19561085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.025155
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