ERK5 Activity Is Required for Nerve Growth Factor-induced Neurite Outgrowth and Stabilization of Tyrosine Hydroxylase in PC12 Cells

Extracellular signal-regulated kinases (ERKs) play important physiological roles in proliferation, differentiation, and gene expression. ERK5 is approximately twice the size of ERK1/2, and its amino-terminal half contains the kinase domain that shares homology with ERK1/2 and TEY activation motif, w...

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Bibliografiske detaljer
Main Authors: Obara, Yutaro, Yamauchi, Arata, Takehara, Shin, Nemoto, Wataru, Takahashi, Maho, Stork, Philip J. S., Nakahata, Norimichi
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2009
Fag:
Mechanisms of Signal Transduction
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749131/
https://ncbi.nlm.nih.gov/pubmed/19581298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.027821
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