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Deglutathionylation of 2-Cys Peroxiredoxin Is Specifically Catalyzed by Sulfiredoxin

Reversible protein glutathionylation plays a key role in cellular regulation and cell signaling and protects protein thiols from hyperoxidation. Sulfiredoxin (Srx), an enzyme that catalyzes the reduction of Cys-sulfinic acid derivatives of 2-Cys peroxiredoxins (2-Cys Prxs), has been shown to catalyz...

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Detalles Bibliográficos
Main Authors: Park, Ji Won, Mieyal, John J., Rhee, Sue Goo, Chock, P. Boon
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749110/
https://ncbi.nlm.nih.gov/pubmed/19561357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.021394
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