Modulating Estrogen Receptor-related Receptor-α Activity Inhibits Cell Proliferation

High expression of the estrogen receptor-related receptor (ERR)-α in human tumors is correlated to a poor prognosis, suggesting an involvement of the receptor in cell proliferation. In this study, we show that a synthetic compound (XCT790) that modulates the activity of ERRα reduces the proliferatio...

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Bibliographic Details
Main Authors: Bianco, Stéphanie, Lanvin, Olivia, Tribollet, Violaine, Macari, Claire, North, Sophie, Vanacker, Jean-Marc
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2009
Subjects:
Mechanisms of Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749102/
https://ncbi.nlm.nih.gov/pubmed/19546226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.028191
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