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Amyloid-β(1-42) Fibrillar Precursors are Optimal for Inducing Tumor Necrosis Factor-α Production in the THP-1 Human Monocytic Cell Line

Pathological studies have determined that fibrillar forms of amyloid-beta protein (Aβ) comprise the characteristic neuritic plaques in Alzheimer’s disease (AD). These studies have also revealed significant inflammatory markers such as activated microglia and cytokines surrounding the plaques. Althou...

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Sonraí Bibleagrafaíochta
Main Authors: Ajit, Deepa, Udan, Maria L. D., Paranjape, Geeta, Nichols, Michael R.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749082/
https://ncbi.nlm.nih.gov/pubmed/19694428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9003777
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