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CAP37-derived antimicrobial peptides have in vitro antiviral activity against adenovirus and herpes simplex virus type 1

PURPOSE: The antiviral activity of an established antibacterial CAP37 domain and its extracellular mechanism of action were investigated. METHODS: CAP37-derived peptides modified to assess the importance of disulfide bonds were evaluated in cytotoxicity, and antiviral assays (direct time kill, dose-...

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Bibliographic Details
Main Authors: Gordon, Y. Jerold, Romanowski, Eric G., Shanks, Robert M. Q., Yates, Kathleen A., Hinsley, Heather, Pereira, H. Anne
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749063/
https://ncbi.nlm.nih.gov/pubmed/19274533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/02713680802714066
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