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Mutations at codons 178, 200-129, and 232 contributed to the inherited prion diseases in Korean patients
BACKGROUND: Polymorphisms of the human prion protein gene (PRNP) contribute to the genetic determinants of Creutzfeldt-Jakob disease (CJD). Numerous polymorphisms in the promoter regions as well as the open reading frame of PRNP were investigated. Greater than 90% of Korean, Chinese, and Japanese ca...
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| Hauptverfasser: | , , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2749045/ https://ncbi.nlm.nih.gov/pubmed/19698114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-9-132 |
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