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Alcohol self-administration acutely stimulates the hypothalamic-pituitary-adrenal axis, but alcohol dependence leads to a dampened neuroendocrine state

Clinical studies link disruption of the neuroendocrine stress system with alcoholism, but remaining unknown is whether functional differences in the hypothalamic-pituitary-adrenal (HPA) axis precede alcohol abuse and dependence or result from chronic exposure to this drug. Using an operant self-admi...

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Detalhes bibliográficos
Main Authors: Richardson, Heather N., Lee, Soon Y., O’Dell, Laura E., Koob, George F., Rivier, Catherine L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748838/
https://ncbi.nlm.nih.gov/pubmed/18979677
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