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Should peripheral CB(1) cannabinoid receptors be selectively targeted for therapeutic gain?

Endocannabinoids, endogenous lipid ligands of cannabinoid receptors, mediate a variety of effects similar to those of marijuana. Cannabinoid CB(1) receptors are highly abundant in the brain and mediate psychotropic effects, which limits their value as a potential therapeutic target. There is growing...

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Autori principali: Kunos, George, Osei-Hyiaman, Douglas, Bátkai, Sándor, Sharkey, Keith A., Makriyannis, Alexandros
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748782/
https://ncbi.nlm.nih.gov/pubmed/19042036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2008.10.001
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