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Thioredoxin Reductase Is Essential for Protection of Neisseria gonorrhoeae against Killing by Nitric Oxide and for Bacterial Growth during Interaction with Cervical Epithelial Cells

In Neisseria gonorrhoeae, the MerR family transcription factor NmlR activates 3 operons in response to disulfide stress. In the present study, we show that trxB, a monocistronic operon under the control of NmlR, encodes a functional thioredoxin reductase. It is shown that neisserial TrxB has biochem...

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Autors principals: Potter, Adam J., Kidd, Stephen P., Edwards, Jennifer L., Falsetta, Megan L., Apicella, Michael A., Jennings, Michael P., McEwan, Alastair G.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748770/
https://ncbi.nlm.nih.gov/pubmed/19032106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/595737
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