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Thioredoxin Reductase Is Essential for Protection of Neisseria gonorrhoeae against Killing by Nitric Oxide and for Bacterial Growth during Interaction with Cervical Epithelial Cells

In Neisseria gonorrhoeae, the MerR family transcription factor NmlR activates 3 operons in response to disulfide stress. In the present study, we show that trxB, a monocistronic operon under the control of NmlR, encodes a functional thioredoxin reductase. It is shown that neisserial TrxB has biochem...

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Detalhes bibliográficos
Main Authors: Potter, Adam J., Kidd, Stephen P., Edwards, Jennifer L., Falsetta, Megan L., Apicella, Michael A., Jennings, Michael P., McEwan, Alastair G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748770/
https://ncbi.nlm.nih.gov/pubmed/19032106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/595737
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