Toxicology Study of Repeat Intracerebral Administration of a Measles Virus Derivative Producing Carcinoembryonic Antigen in Rhesus Macaques in Support of a Phase I/II Clinical Trial for Patients with Recurrent Gliomas

Gliomas have a dismal prognosis, with the median survival of patients with the most common histology, glioblastoma multiforme, being only 12–15 months. Development of novel therapeutic agents is urgently needed. We have previously demonstrated that oncolytic measles virus strains derived from the Ed...

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Detalhes bibliográficos
Main Authors: Myers, Rae, Harvey, Mary, Kaufmann, Timothy J., Greiner, Suzanne M., Krempski, James W., Raffel, Corey, Shelton, Steven E., Soeffker, Diane, Zollman, Paula, Federspiel, Mark J., Blanco, Michael, Galanis, Evanthia
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2008
Assuntos:
Scientific Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748764/
https://ncbi.nlm.nih.gov/pubmed/18576918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2008.035
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