From Disease Association to Risk Assessment: An Optimistic View from Genome-Wide Association Studies on Type 1 Diabetes

Genome-wide association studies (GWAS) have been fruitful in identifying disease susceptibility loci for common and complex diseases. A remaining question is whether we can quantify individual disease risk based on genotype data, in order to facilitate personalized prevention and treatment for compl...

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Hlavní autoři: Wei, Zhi, Wang, Kai, Qu, Hui-Qi, Zhang, Haitao, Bradfield, Jonathan, Kim, Cecilia, Frackleton, Edward, Hou, Cuiping, Glessner, Joseph T., Chiavacci, Rosetta, Stanley, Charles, Monos, Dimitri, Grant, Struan F. A., Polychronakos, Constantin, Hakonarson, Hakon
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2009
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748686/
https://ncbi.nlm.nih.gov/pubmed/19816555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000678
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