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Mitotic bookmarking of formerly active genes: keeping epigenetic memories from fading

In order for cell lineages to be maintained, daughter cells must have the same patterns of gene expression as the cells from which they were divided so that they can have the same phenotypes. However, during mitosis transcription ceases, chromosomal DNA is compacted, and most sequence-specific bindi...

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Bibliographic Details
Main Authors: Sarge, Kevin D., Park-Sarge, Ok-Kyong
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748302/
https://ncbi.nlm.nih.gov/pubmed/19221503
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