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CGHnormaliter: an iterative strategy to enhance normalization of array CGH data with imbalanced aberrations

BACKGROUND: Array comparative genomic hybridization (aCGH) is a popular technique for detection of genomic copy number imbalances. These play a critical role in the onset of various types of cancer. In the analysis of aCGH data, normalization is deemed a critical pre-processing step. In general, aCG...

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書誌詳細
主要な著者: van Houte, Bart PP, Binsl, Thomas W, Hettling, Hannes, Pirovano, Walter, Heringa, Jaap
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748095/
https://ncbi.nlm.nih.gov/pubmed/19709427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-10-401
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