Impact of HLA in Mother and Child on Disease Progression of Pediatric Human Immunodeficiency Virus Type 1 Infection

A broad Gag-specific CD8(+) T-cell response is associated with effective control of adult human immunodeficiency virus (HIV) infection. The association of certain HLA class I molecules, such as HLA-B*57, -B*5801, and -B*8101, with immune control is linked to mutations within Gag epitopes presented b...

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Hlavní autoři: Thobakgale, Christina F., Prendergast, Andrew, Crawford, Hayley, Mkhwanazi, Nompumelelo, Ramduth, Danni, Reddy, Sharon, Molina, Claudia, Mncube, Zenele, Leslie, Alasdair, Prado, Julia, Chonco, Fundi, Mphatshwe, Wendy, Tudor-Williams, Gareth, Jeena, Prakash, Blanckenberg, Natasha, Dong, Krista, Kiepiela, Photini, Coovadia, Hoosen, Ndung'u, Thumbi, Walker, Bruce D., Goulder, Philip J. R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2009
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748050/
https://ncbi.nlm.nih.gov/pubmed/19605475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00921-09
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