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Selective-Advantage Profile of Human Immunodeficiency Virus Type 1 Integrase Mutants Explains In Vivo Evolution of Raltegravir Resistance Genotypes

The emergence of human immunodeficiency virus type 1 resistance to raltegravir, an integrase strand transfer inhibitor, follows distinct and independent genetic pathways, among which the N155H and Q148HKR pathways are the most frequently encountered in treated patients. After prolonged viral escape,...

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Bibliografski detalji
Glavni autori: Quercia, Romina, Dam, Elisabeth, Perez-Bercoff, Danielle, Clavel, François
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747997/
https://ncbi.nlm.nih.gov/pubmed/19605484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00894-09
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