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Cross Talk between Receptor Guanylyl Cyclase C and c-src Tyrosine Kinase Regulates Colon Cancer Cell Cytostasis

Increased activation of c-src seen in colorectal cancer is an indicator of a poor clinical prognosis, suggesting that identification of downstream effectors of c-src may lead to new avenues of therapy. Guanylyl cyclase C (GC-C) is a receptor for the gastrointestinal hormones guanylin and uroguanylin...

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Autors principals: Basu, Nirmalya, Bhandari, Rashna, Natarajan, Vivek T., Visweswariah, Sandhya S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747985/
https://ncbi.nlm.nih.gov/pubmed/19620276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00001-09
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