The Trehalose Synthesis Pathway Is an Integral Part of the Virulence Composite for Cryptococcus gattii

The trehalose pathway is essential for stress tolerance and virulence in fungi. We investigated the importance of this pathway for virulence of the pathogenic yeast Cryptococcus gattii using the highly virulent Vancouver Island, Canada, outbreak strain R265. Three genes putatively involved in trehal...

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Detalhes bibliográficos
Main Authors: Ngamskulrungroj, Popchai, Himmelreich, Uwe, Breger, Julia A., Wilson, Christabel, Chayakulkeeree, Methee, Krockenberger, Mark B., Malik, Richard, Daniel, Heide-Marie, Toffaletti, Dena, Djordjevic, Julianne T., Mylonakis, Eleftherios, Meyer, Wieland, Perfect, John R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747965/
https://ncbi.nlm.nih.gov/pubmed/19651856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00565-09
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