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Chlamydia muridarum-Specific CD4 T-Cell Clones Recognize Infected Reproductive Tract Epithelial Cells in an Interferon-Dependent Fashion

During natural infections Chlamydia trachomatis urogenital serovars replicate predominantly in the epithelial cells lining the reproductive tract. This tissue tropism poses a unique challenge to host cellar immunity and future vaccine development. In the experimental mouse model, CD4 T cells are nec...

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Main Authors: Jayarapu, Krupakar, Kerr, Micah S., Katschke, Adrian, Johnson, Raymond M.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747947/
https://ncbi.nlm.nih.gov/pubmed/19667042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00491-09
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