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Actin Dynamics and Rho GTPases Regulate the Size and Formation of Parasitophorous Vacuoles Containing Coxiella burnetii

Q fever is a disease caused by Coxiella burnetii. In the host cell, this pathogen generates a large parasitophorous vacuole (PV) with lysosomal characteristics. Here we show that F-actin not only is recruited to but also is involved in the formation of the typical PV. Treatment of infected cells wit...

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Detalhes bibliográficos
Main Authors: Aguilera, Milton, Salinas, Romina, Rosales, Eliana, Carminati, Sergio, Colombo, Maria I., Berón, Walter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747940/
https://ncbi.nlm.nih.gov/pubmed/19635823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00301-09
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