Identification of a Gingipain-Sensitive Surface Ligand of Porphyromonas gingivalis That Induces Toll-Like Receptor 2- and 4-Independent NF-κB Activation in CHO Cells

Porphyromonas gingivalis is a major periodontal pathogen that has the pathogenic proteinases Arg-specific gingipain and Lys-specific gingipain. We previously found that a cell surface component on P. gingivalis is able to induce Toll-like receptor 2 (TLR2)- and TLR4-independent signaling in 7.19 cel...

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Detalhes bibliográficos
Main Authors: Haruyama, Koki, Yoshimura, Atsutoshi, Naito, Mariko, Kishimoto, Mami, Shoji, Mikio, Abiko, Yoshimitsu, Hara, Yoshitaka, Nakayama, Koji
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747925/
https://ncbi.nlm.nih.gov/pubmed/19667049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00140-09
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