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Binding site of ABC transporter homology models confirmed by ABCB1 crystal structure
The human ATP-binding cassette (ABC) transporters ABCB1, ABCC4 and ABCC5 are involved in resistance to chemotherapeutic agents. Here we present molecular models of ABCB1, ABCC4 and ABCC5 by homology based on a wide open inward-facing conformation of Escherichia coli MsbA, which were constructed in o...
Gorde:
| Egile Nagusiak: | , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
BioMed Central
2009
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2747915/ https://ncbi.nlm.nih.gov/pubmed/19732422 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4682-6-20 |
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