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Significant Bias against the ACA Triplet in the tmRNA Sequence of Escherichia coli K-12

The toxin MazF in Escherichia coli cleaves single-stranded RNAs specifically at ACA sequences. MazF overexpression virtually eliminates all cellular mRNAs to completely block protein synthesis. However, protein synthesis can continue on an mRNA that is devoid of ACA triplets. The finding that riboso...

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Detalhes bibliográficos
Main Authors: Baik, Sarah, Inoue, Koichi, Ouyang, Ming, Inouye, Masayori
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747887/
https://ncbi.nlm.nih.gov/pubmed/19633073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00699-09
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