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Understanding diversity of human innate immunity receptors: analysis of surface features of leucine-rich repeat domains in NLRs and TLRs

BACKGROUND: The human innate immune system uses a system of extracellular Toll-like receptors (TLRs) and intracellular Nod-like receptors (NLRs) to match the appropriate level of immune response to the level of threat from the current environment. Almost all NLRs and TLRs have a domain consisting of...

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Hlavní autoři: Istomin, Andrei Y, Godzik, Adam
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747839/
https://ncbi.nlm.nih.gov/pubmed/19728889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-10-48
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