Sustained antiproliferative mechanisms by RB24, a targeted precursor of multiple inhibitors of epidermal growth factor receptor and a DNA alkylating agent in the A431 epidermal carcinoma of the vulva cell line

Recently, with the purpose of enhancing the potency of epidermal growth factor receptor (EGFR)-based therapies, we designed a novel strategy termed ‘Cascade-release targeting’ that seeks to develop molecules capable of degrading to multiple tyrosine kinase (TK) inhibitors and highly reactive electro...

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Bibliographic Details
Main Authors: Banerjee, R, Rachid, Z, Qiu, Q, McNamee, J P, Tari, A M, Jean-Claude, B J
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2004
Subjects:
Molecular and Cellular Pathology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747684/
https://ncbi.nlm.nih.gov/pubmed/15365562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602098
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