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MicroRNA Mirn140 modulates Pdgf signaling during palatogenesis

Disruption of signaling pathways such as those mediated by Shh or Pdgf causes craniofacial disease, including cleft palate. The role that microRNAs play in modulating palatogenesis, however, is completely unknown. We show, in zebrafish, that the microRNA Mirn140 negatively regulates Pdgf signaling d...

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Detalhes bibliográficos
Main Authors: Eberhart, Johann K., He, Xinjun, Swartz, Mary E., Yan, Yi-Lin, Song, Hao, Boling, Taylor C., Kunerth, Allison K., Walker, Macie B., Kimmel, Charles B., Postlethwait, John H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747601/
https://ncbi.nlm.nih.gov/pubmed/18264099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.82
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