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Sp1 Is Required for Glucose-induced Transcriptional Regulation of Mouse Vesicular Glutamate Transporter 2 Gene

BACKGROUND & AIMS: Vesicular glutamate transporter (VGLUT) has been reported to be involved in glucose-induced insulin secretion. It has been shown that glucose stimulates the expression of VGLUT isoform 2 (VGLUT2) in β cells via transcriptional mechanism. In this study, we identified the mouse...

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Detalhes bibliográficos
Main Authors: Li, Tao, Bai, Liqun, Li, Jing, Igarashi, Suzu, Ghishan, Fayez K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747381/
https://ncbi.nlm.nih.gov/pubmed/18440316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2008.02.076
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