Lack of TNFα expression protects anaplastic lymphoma kinase-positive T-cell lymphoma (ALK+ TCL) cells from apoptosis

Here we report that T-cell lymphomas characterized by the expression of anaplastic lymphoma kinase (ALK+ TCL) fail to express the TNFα and frequently display DNA methylation of the TNFα gene promoter. While only a subset of the ALK+ TCL-derived cell lines showed a high degree of the promoter methyla...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Zhang, Qian, Wang, Hong Y., Bhutani, Gauri, Liu, Xiaobin, Paessler, Michele, Tobias, John W., Baldwin, Donald, Swaminathan, Kunchithapadam, Milone, Michael C., Wasik, Mariusz A.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2009
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747206/
https://ncbi.nlm.nih.gov/pubmed/19717436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0907070106
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы