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Allosteric collaboration between elongation factor G and the ribosomal L1 stalk directs tRNA movements during translation

Determining the mechanism by which tRNAs rapidly and precisely transit through the ribosomal A, P, and E sites during translation remains a major goal in the study of protein synthesis. Here, we report the real-time dynamics of the L1 stalk, a structural element of the large ribosomal subunit that i...

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Detalhes bibliográficos
Main Authors: Fei, Jingyi, Bronson, Jonathan E., Hofman, Jake M., Srinivas, Rathi L., Wiggins, Chris H., Gonzalez, Ruben L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747183/
https://ncbi.nlm.nih.gov/pubmed/19717422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908077106
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