Lack of Self-Administration of Cocaine in Dopamine D(1) Receptor Knock-Out Mice

Evidence suggests a critical role for dopamine in the reinforcing effects of cocaine in rats and primates. However, self-administration has been less often studied in the mouse species, and, to date, “knock-out” of individual dopamine-related genes in mice has not been reported to reduce the reinfor...

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Main Authors: Caine, S. Barak, Thomsen, Morgane, Gabriel, Kara I., Berkowitz, Jill S., Gold, Lisa H., Koob, George F., Tonegawa, Susumu, Zhang, Jianhua, Xu, Ming
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2007
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747091/
https://ncbi.nlm.nih.gov/pubmed/18045908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2284-07.2007
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