HIV-1 Vpr Triggers Natural Killer Cell–Mediated Lysis of Infected Cells through Activation of the ATR-Mediated DNA Damage Response

Natural killer (NK) cells are stimulated by ligands on virus-infected cells. We have recently demonstrated that NK cells respond to human immunodeficiency virus type-1 (HIV-1)-infected autologous T-cells, in part, through the recognition of ligands for the NK cell activating receptor NKG2D on the su...

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Bibliografiske detaljer
Main Authors: Ward, Jeffrey, Davis, Zachary, DeHart, Jason, Zimmerman, Erik, Bosque, Alberto, Brunetta, Enrico, Mavilio, Domenico, Planelles, Vicente, Barker, Edward
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2009
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747015/
https://ncbi.nlm.nih.gov/pubmed/19798433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000613
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