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NF-κB activation primes cells to a pro-inflammatory polarized response to a TLR7 agonist
Toll-like receptor 7 (TLR7) mediates anti-viral immunity by recognizing ssRNA viruses. Small molecular weight TLR7 agonists have been approved, or are being evaluated, for treatment of cancers or infectious diseases. Although TLR7 is predominantly expressed in a restricted set of immune cell types i...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2746977/ https://ncbi.nlm.nih.gov/pubmed/19426145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20090013 |
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