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Advanced Osteoarthritis in Humans Is Associated With Altered Collagen VI Expression and Upregulation of ER-stress Markers Grp78 and Bag-1

To test the hypothesis that a perturbation of endoplasmic reticulum (ER) function is involved in the pathogenesis of osteoarthritis (OA), articular cartilage was isolated from non-OA patients secondary to resection of osteo- or chondrosarcomas. Intra-joint samples of minimal and advanced osteoarthri...

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Autors principals: Nugent, Ashleigh E., Speicher, Danielle M., Gradisar, Ian, McBurney, Denise L., Baraga, Anthony, Doane, Kathleen J., Horton, Walter E.
Format: Artigo
Idioma:Inglês
Publicat: Histochemical Society 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746726/
https://ncbi.nlm.nih.gov/pubmed/19546472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1369/jhc.2009.953893
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