Drug-induced activation of dopamine D(1) receptor signaling and inhibition of class I/II histone deacetylase induces chromatin remodeling in reward circuitry and modulates cocaine-related behaviors

Chromatin remodeling, including histone modification, is involved in stimulant-induced gene expression and addiction behavior. To further explore the role of dopamine D(1) receptor signaling, we measured cocaine-related locomotor activity and place preference in mice pre-treated for up to 10 days wi...

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Hlavní autoři: Schroeder, Frederick A., Penta, Krista L., Matevossian, Anouch, Jones, Sara R., Konradi, Christine, Tapper, Andrew R., Akbarian, Schahram
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746694/
https://ncbi.nlm.nih.gov/pubmed/18288092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2008.15
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