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Migratory and lymphoid-resident dendritic cells cooperate in lymph nodes for efficient CD4(+) T cell priming
To initiate an adaptive immune response, rare antigen-specific naïve CD4(+) T cells must interact with equally rare dendritic cells (DCs) bearing cognate peptide-MHC complexes. Lymph nodes (LN) draining the site of antigen entry are populated by lymphoid-resident DCs as well as DCs that have immigra...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2746692/ https://ncbi.nlm.nih.gov/pubmed/18951047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2008.08.013 |
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