Effects of ageing and exercise training on eNOS uncoupling in skeletal muscle resistance arterioles

Reduced availability of tetrahydrobiopterin (BH(4)) contributes to the age-related decline of nitric oxide (NO)-mediated vasodilatation of soleus muscle arterioles. Depending on availability of substrate and/or necessary co-factors, endothelial nitric oxide synthase (eNOS) can generate NO and/or sup...

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Detalhes bibliográficos
Main Authors: Sindler, Amy L, Delp, Michael D, Reyes, Rafael, Wu, Guoyao, Muller-Delp, Judy M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2009
Assuntos:
Cardiovascular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746616/
https://ncbi.nlm.nih.gov/pubmed/19528246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.172221
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