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Characterization of cell death induced by vinflunine, the most recent Vinca alkaloid in clinical development

Vinflunine, the most recent Vinca alkaloid in clinical development, demonstrated superior antitumour activity to other Vincas in preclinical tumour models. This study aimed to define its molecular mechanisms of cell killing in both parental sensitive and vinflunine-resistant P388 leukaemia cells. Vi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kruczynski, A, Etiévant, C, Perrin, D, Chansard, N, Duflos, A, Hill, B T
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746541/
https://ncbi.nlm.nih.gov/pubmed/11857026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600025
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