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Carcinoma Produced Factors Activate Myeloid Cells via TLR2 to Stimulate Metastasis

Metastatic progression depends on genetic alterations intrinsic to cancer cells as well as the inflammatory microenvironment of advanced tumors1,2. To understand how cancer cells affect the inflammatory microenvironment, we conducted a biochemical screen for macrophage activating factors secreted by...

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Detalhes bibliográficos
Main Authors: Kim, Sunhwa, Takahashi, Hiroyuki, Lin, Wan-Wan, Descargues, Pascal, Grivennikov, Sergei, Kim, Youngjun, Luo, Jun-Li, Karin, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746432/
https://ncbi.nlm.nih.gov/pubmed/19122641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07623
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