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Two allelic isoforms of the serotonin transporter from Schistosoma mansoni display electrogenic transport and high selectivity for serotonin

The human blood fluke Schistosoma mansoni is the primary cause of schistosomiasis, a debilitating disease that affects 200 million individuals in over 70 countries. The biogenic amine serotonin is essential for the survival of the parasite and serotonergic proteins are potential novel drug targets f...

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Detalhes bibliográficos
Main Authors: Fontana, Andréia C. K., Sonders, Mark S., Pereira-Junior, Olavo S., Knight, Matty, Javitch, Jonathan A., Rodrigues, Vanderlei, Amara, Susan G., Mortensen, Ole V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746412/
https://ncbi.nlm.nih.gov/pubmed/19549517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2009.06.023
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