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Cautionary Insights on Knockout Mouse Studies: The Gene or Not the Gene?
Gene modification technologies play a vital role in the study of biological systems and pathways. Although there is widespread and beneficial use of genetic mouse models, potential shortcomings of gene targeting technology exist, and are not always taken into consideration. Oversights associated wit...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2746382/ https://ncbi.nlm.nih.gov/pubmed/18822367 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2008.09.001 |
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